Samworth depicts the fear and wonder of the natural world in her highly detailed drawings of imaginary places. She explores the spiritual questions and existential anxiety raised by observing nature and a rapidly changing environment. Her background in printmaking and illustration are evident in her scratchboard engravings, in which each mark is made with precision.

Samworth grew up in the suburbs of Washington, DC and was part of a politically active community of artists and musicians. Her work has responded to environmental subjects for decades, evolving to reflect new experiences, like volunteering on organic farms in Turkey and Spain and working as a translator for a hiking guide in Brazil.

She exhibits regularly, has illustrated several books, and teaches the Art of Natural History.